Abstract
Hinamizawa Syndrome is a distinct neuropsychiatric syndrome confined to the population of Hinamizawa, manifesting as anxiety, persecutory delusions, self-harm impulses, perceptual abnormalities, and terminal violent behavior. Based on five consecutive years of field observations, clinical records, and anatomical analyses, this study systematically organizes the epidemiological characteristics, graded progression, biological basis, and environmental triggers of this syndrome. Results indicate that the syndrome is highly correlated with specific parasitic microorganisms and collective psychological stress, and significantly worsens under conditions of social isolation, displacement from ancestral lands, or disruption of religious beliefs. This paper proposes a five-stage progression model and comprehensive intervention strategy, providing a theoretical foundation for subsequent treatment and management.

